Exercise-induced myokines in health and metabolic diseases
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چکیده
منابع مشابه
Exercise-induced myokines in health and metabolic diseases
Skeletal muscle has been emerging as a research field since the past 2 decades. Contraction of a muscle, which acts as a secretory organ, stimulates production, secretion, and expression of cytokines or other muscle fiber-derived peptides, i.e., myokines. Exercise-induced myokines influence crosstalk between different organs in an autocrine, endocrine, or paracrine fashion. Myokines are recentl...
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Physical inactivity has recently been identified as a major and independent risk factor for the development of dementia and cognitive decline. In addition to the effect of exercise with regard to protection against neurodegenerative diseases, it is well-established that physical inactivity increases the risk of type 2 diabetes, cardiovascular diseases (CVD), colon cancer and postmenopausal brea...
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Chronic inflammation is involved in the pathogenesis of insulin resistance, atherosclerosis, neurodegeneration, and tumour growth. Regular exercise offers protection against type 2 diabetes, cardiovascular diseases, colon cancer, breast cancer, and dementia. Evidence suggests that the protective effect of exercise may to some extent be ascribed to the antiinflammatory effect of regular exercise...
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During the past 20 yr, it has been well documented that exercise has a profound effect on the immune system. With the discovery that exercise provokes an increase in a number of cytokines, a possible link between skeletal muscle contractile activity and immune changes was established. For most of the last century, researchers sought a link between muscle contraction and humoral changes in the f...
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Milène Catoire, Marco Mensink, Eric Kalkhoven, Patrick Schrauwen, and Sander Kersten Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, Wageningen, the Netherlands; Department of Metabolic Diseases, University Medical Centre Utrecht, Utrecht, the Netherlands; and Department of Human Biology, Maastricht University Medical Centre, Maastricht, the Netherl...
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ژورنال
عنوان ژورنال: Integrative Medicine Research
سال: 2014
ISSN: 2213-4220
DOI: 10.1016/j.imr.2014.09.007